EDIT Lab / Emerging Diagnostics and Innovative Therapeutics
Our sensors read blood without dyes, labels, or sample prep. Some detect a single molecule binding at an electrode. Others track what a whole sample does as it clots.
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Blood moves through an electrode-instrumented channel at a shear rate we set. Clot formation and dissolution are tracked electrically while they happen.
Dielectric spectroscopy, under flowBlood sits between two electrodes at rest. As fibrin forms and the clot contracts, its electrical properties change across a sweep of frequencies.
Dielectric spectroscopy, kHz to MHzA target molecule binds at an electrode functionalized with 2D materials or imprinted polymers. The impedance of that interface shifts when it does.
Electrochemical impedance
The EDIT Lab sits in Biological and Agricultural Engineering at Louisiana State University and was established in November 2024. We build electrical and microfluidic sensors for blood and other complex samples, and work toward turning those measurements into diagnostics people can actually afford.
Two things carry information here: what binds at the electrode, and what the sample itself is doing. Depending on the question, we measure one, the other, or both in the same sample.
The second half of the lab's name is therapeutic. Electrical devices can deliver as well as measure, and Dr. Maji worked on in vivo electroporation for targeted delivery before coming to LSU.
Research in the EDIT Lab is supported in part by the American Heart Association.
BMES Annual Meeting, Orlando. Ahnaf Tahmid and Jithin Thomas Chacko each give a talk in the Thrombosis and Hemostasis session, 1:15 to 2:45 PM, and Jithin also presents a poster that day.
Seven new undergraduate researchers join the lab: Connor, Sarah, Cohen, Lacie, Rylie, Benson, and Samantha.
Collaborative work on DNA-based delivery of incretin receptor agonists using MYO Technology is published in Molecular Therapy Nucleic Acids.
Dr. Maji receives an American Heart Association Rapid Impact Research Award.